Objective: Fertility loss due to cancer treatment can be a devastating experience for women and the couple. Undergoing fertility preservation can be a complex decision from both a medical and emotional point of view. The aim of the present study was to evaluate which socio-demographic and psychological factors predict a high motivation to undergo fertility preservation.Methods: Fifty-eight female cancer patients who accessed an Oncofertility Unit completed: a questionnaire to collect socio-demographic characteristics and the level of motivation, the Beck-Depression Inventory-II, the (...) State-Trait Anxiety Inventory-Y, and the Fertility Problem Inventory.Results: Almost half of the sample declared a high motivation. At multiple logistic regression analysis only the “Need for parenthood” subscale of the FPI predicted a high motivation. We alternatively evaluated as possible predictor the construct “Representations about the importance of parenthood” in place of the two separate subscales. At multiple logistic regression analysis, only this variable predicted a high motivation to undergo fertility preservation.Conclusion: The most important predictor of a high motivation to undergo fertility preservation is the individual desire for parenthood. This implies that, regardless of socio-demographic characteristics, any woman of childbearing age should receive an appropriate counseling about fertility preservation. (shrink)

Di Rosa Calzecchi Onesti (1916-2011) si conoscono e si apprezzano le traduzioni, tutt’ora considerate punti di riferimento, di Iliade (1950), Odissea (1963) ed Eneide (1967); assai poco note sono, per contro, le sue ricerche di carattere filologico condotte sul testo del poema virgiliano. In particolare, a Calzecchi si deve una tesi di laurea, discussa a Bologna nel 1940 sotto la guida di Gino Funaioli e dedicata alla spinosa questione della possibile presenza di residue varianti d’autore nel testo dell’Eneide. Parte dei (...) risultati confluì nell’edizione critica curata per l’Istituto Editoriale Italiano nel 1962, una manciata di anni prima della ben più nota traduzione per Einaudi. Nonostante la questione della variantistica d’autore nel testo di Virgilio sia stata da tempo superata dalla critica, un approfondimento può fornire, da un lato, un utile documento di storia degli studi: la questione della variantistica d’autore, nella tradizione dell’Eneide come in quella di altri autori classici, era, all’epoca in cui Calzecchi lavorò, tema assai dibattuto. Inoltre, almeno uno dei criteri individuati dalla giovane studiosa nella sua analisi può essere applicato con profitto anche a tradizioni in cui la presenza di varianti d’autore è verosimile o accertata. (shrink)

After its rise, in the years of the George W. Bush Jr.’s presidency, neoconservatism seemed to collapse under the weight of its utopian ambition to dictate the new rules of the internal and international political order, to stem the conflicts and processes of disruption of the liberal order as it had been defined since the Second World War. Going through the various contributions of the monographic issue, this introduction highlights the historical and political reasons that make neoconservatism an idea whose (...) parable and movements are of great importance to understand the crisis of liberalism and the current role of the neoliberalism. (shrink)

: This contribution aims to address epistemological issues at the crossroads of philosophy of science and psychiatry by reflecting on the notions of organization and resilience. Referring to the debate on the notion of “organization” and its explanatory relevance in philosophical neo-mechanistic theories, I consider how such positions hold up when tentatively applied to the mental health context. More specifically, I show how reflections on psychiatric resilience, cognitive reserve, and accommodation strategies challenge attempts to embrace a mechanistic perspective on mental (...) disorders. A deeper focus on these aspects of mental health is relevant to theoretical discussions on explanatory models as well as for clinical practice, diagnosis, and treatment. Keywords: Psychiatric resilience; Cognitive Reserve; Organization; Mechanism Il ruolo esplicativo dell’organizzazione e la resilienza psichiatrica: sfide ad un approccio meccanicistico alla malattia mentale Riassunto: Questo articolo intende discutere alcuni temi epistemologici all’incrocio tra la filosofia della scienza e la psichiatria, riflettendo sulle nozioni di organizzazione e resilienza. Muovendo dalle riflessioni sulla nozione di “organizzazione” sviluppate nell’ambito delle teorie neo-meccaniciste, e dalla difesa del suo ruolo esplicativo, il lavoro analizza la possibilità di estendere alcune posizioni relative alla spiegazione scientifica al contesto delle scienze della salute mentale. Più nello specifico, si illustra come le indagini sulla resilienza psichiatrica, la riserva cognitiva e le strategie di compensazione possano mettere in discussione i tentativi di abbracciare una prospettiva meccanicistica quando si affronta il tema del disturbo psichiatrico. Una maggiore attenzione ai suddetti filoni di ricerca può avere un impatto significativo sia sulla discussione relativa ai modelli teorici di spiegazione della malattia mentale sia sui processi clinici di diagnosi e terapia. Parole chiave: Resilienza psichiatrica; Riserva cognitiva; Organizzazione; Meccanicismo. (shrink)

: Hypotheses are the first step in scientific and clinical enquiry. They guide all of the subsequent steps in an investigation, and influence data collection, analysis, and interpretation. But how do we build scientific and clinical hypotheses? In both research and clinical contexts, a professional’s idiosyncratic way of perceiving reality, her prejudices and biases will influence the process of hypothesis formulation. We compare the process of formulating a scientific hypothesis in the field of neuroscience with the process of building a (...) clinical hypothesis in the systemic therapeutic approach. This comparison is intended to highlight the biases that influence researchers and clinicians when formulating hypotheses. Our aim is to raise awareness of the most common biases, and to point out how the tools developed by clinicians could be useful to researchers, and vice versa. Keywords: Hypotheses; Clinical Psychology; Neuroscience; Bias; Interdisciplinary Approach La costruzione di ipotesi nella psicologia clinica e nella neuroscienza: similitudini e differenze Riassunto: Le ipotesi sono il primo passo della ricerca scientifica e clinica. Sono la guida di tutti i passi successivi e influenzano la racconta dei dati, la loro analisi e l’interpretazione. Come si costruiscono le ipotesi scientifiche e quelle cliniche? Sia nell’ambito della ricerca che nei contesti clinici le idiosincrasie con cui un professionista percepisce la realtà, i suoi bias e pregiudizi influenzeranno il processo di formulazione dell’ipotesi. In questa sede intendiamo confrontare il processo di formulazione di un’ipotesi scientifica nel campo della neuroscienza e il processo di costruzione dell’ipotesi clinica nell’approccio della terapia sistemica. Questo confronto vuole mettere in luce i bias che influenzano ricercatori e terapeuti nella formulazione delle ipotesi. Il nostro scopo è mettere in luce gli errori sistematici più comuni, mostrando come gli strumenti sviluppati dai terapeuti possano essere utili per i ricercatori e viceversa. Parole chiave: Ipotesi; Psicologia clinica; Neuroscienza; Bias; Approccio interdisciplinare. (shrink)

The increasing prominence of men’s studies in the academic panorama has allowed for further investigation not only on women’s, but also on men’s literary identities. The Ibis Trilogy by Amitav Ghosh offers new insights on the subject by staging several queer masculinities. The present essay analyses the non-conforming identity of Kesri Singh from the perspective of men’s studies. Firstly, the essay compares and contrasts the socially imposed masculinity with Kesri’s divergent one. Secondly, it highlights the strategy deployed by the warrior (...) in order to protect his psychological and physical integrity in a toxic environment. Given the strong historical background of the novels, references are provided to account for the patriarchal context in which Kesri develops. Further sources of discrimination such as race and class are also explored, according to an intersectional feminist approach. Thus, it will be proved that a male gender related discourse covers ample narrative space in the Trilogy; it also reflects the critical opposition by Ghosh to the Western colonialism and Indian caste division. Moreover, it will be exposed the manipulative use of the male gender as an instrument to enforce colonialism and classism. Therefore, the Trilogy presents masculinity as a highly debatable, multifaceted notion which undergoes a negotiation in meaning throughout the novels. This premise leads to a broader definition of the concept, which provides a new, significant viewpoint on the subject. (shrink)

Al centro dell'attenzione degli studiosi nell'ultimo ventennio per l'importanza della testimonianza storica, per il carattere peculiare delle strutture compositive, per varie sfaccettature dell'impostazione ideologica, l'opera di Michele Attaliata non disponeva di un'analisi complessiva né tantomeno di un'edizione critica condotta sulla base degli attuali criteri ecdotici e di una traduzione in una lingua moderna. Lacuna avvertita dai bizantinisti con maggiore evidenza, dal momento che per gli altri storici di primo piano dell'XI secolo, da Michele Psello a Giovanni Scilitza, ci si avvale (...) di strumenti critici agguerriti. Lacuna colmata dal poderoso lavoro di I. Pérez Martín che si presenta come un'edizione dell' Ἱστοϱία di Attaliata, corredata da traduzione in spagnolo, commento, bibliografia, indici, tavole e preceduta da un'ampia introduzione. (shrink)

Publié il y a quinze ans, le livre de Raffaella Sarti est devenu un classique, traduit en plusieurs langues. C’est un des premiers ouvrages qui, s’inscrivant dans la lignée des travaux de Daniel Roche sur « les choses banales » (1997), entendait se livrer à une histoire comparée de la vie matérielle de la fin du xve au début du xixe siècle dans un espace compris entre l’Atlantique et l’Oural et du Cap nord à l’île de Lampedusa. Le but (...) était de faire une histoire de la famille de l’Europe m... (shrink)

L’Italie est l’un des pays de l’Union européenne où l’on fait le moins d’enfants, où le pourcentage de personnes âgées de plus de 65 ans est parmi les plus élevés (en 2008, Italie : 20 % ; Europe à 25 : 17 %), et où la dépense publique pour l’assistance aux personnes âgées est parmi les plus basses (en 2006, Italie : un peu plus de 0,1 % ; Europe à 25 : un peu moins de 0,5 %,). Quel est (...) alors le secret italien? Le « welfare fait maison », c’est-à-dire une troupe d’assistantes domiciliaires p... (shrink)

La letteratura veneziana degli anni Trenta del Cinquecento è caratterizzata da una volontà di reazione nei confronti della tradizione letteraria precedente. Gli effetti delle guerre d’Italia e la conseguente discesa di Carlo V comportò profondi cambiamenti politici e culturali e una decadenza del sistema delle corti. Autori come Aretino, Speroni e Piccolomini furono tra i primi a cogliere questi mutamenti, scrivendo opere che polemizzano nei confronti di testi ambientati a corte come gli Asolani di Bembo e il Cortegiano di Castiglione. (...) Un aspetto che accomuna questa produzione letteraria è rappresentato dal ruolo preminente che viene affidato ai personaggi femminili. Nei Ragionamenti di Aretino, nella Raffaella di Piccolomini e nel Dialogo d’amore di Speroni, le donne diventano lo strumento principale per esprimere opinioni nuove e polemiche nei confronti delle ipocrisie e delle idealizzazioni del mondo della corte. Nel presente articolo, si evidenzieranno gli aspetti più importanti di queste opere, mostrando come la scelta di personaggi femminili non risponda ad una semplice moda letteraria ma derivi piuttosto da ragioni ideologiche. (shrink)

Médecins Sans Frontières is one of the world’s leading humanitarian medical organizations. The increased emphasis in MSF on research led to the creation of an ethics review board in 2001. The ERB has encouraged innovation in the review of proposals and the interaction between the ERB and the organization. This has led to some of the advances in ethics governance described in this paper.

In this book, Roberto Di Ceglie offers an historical, theological, and epistemological investigation exploring how commitments to God and/or the good generate the optimum condition to achieve knowledge. Di Ceglie criticizes the common belief that to attain knowledge, one must always be ready to replace one's convictions with beliefs that appear to be proven. He defends a more comprehensive view, historically exemplified by outstanding Christian thinkers, whereby believers are expected to commit themselves to God and to related beliefs no matter (...) how convincing the evidence contradicting such beliefs appear to be. He also argues that both believers and unbelievers can commit themselves to God and the good, respectively, thereby creating a spiritual turn in epistemology that enables them to generate the best possible condition for conducting rational enquiries and discussion. (shrink)

There is a growing interest in Evald Ilyenkov’s work and its significance for contemporary debates. This interest spans several disciplines. One key thread in Ilyenkov’s ideas concerns a perspective on the relation between biology and psychology. In rejecting crude reductionism and individualism, Ilyenkov put forward a view of mind and personhood as emerging from activity and social practice. In his rejection of brain-bound notions of the mind, Ilyenkov’s ideas bear interesting resonances with current work in 4E cognition. One particularly interesting (...) resonance that has occasionally been noticed are the connections with the enactive approach to life and mind. However, beyond some hints at interesting convergences, there is to date no detailed comparison between the two views. The present article attempts to address this gap, examining both complementarities and possible tensions between the two approaches. Rejecting cognitive views detached from environmental and social processes, the enactive approach, as exemplified by De Jaegher and Di Paolo’s concept of participatory sense-making, emphasises the dynamic constitution of cognition through embodied and situated activities. The article draws parallels between Ilyenkov’s emphasis on historically and culturally situated activity, notably labour, and the enactive understanding of human bodies as dynamically constituted in human activity. The article explores the Ilyenkovian and enactive perspectives on the dialectics of ideality, challenging traditional dualistic views and proposing that the ideal emerges as metastable patterns in the ongoing interactions between world, practices, norms, and bodies. The article concludes by suggesting future research directions for the enactive approach, particularly in areas emphasised by Ilyenkov, such as labour and the mediation of material/cultural artefacts. (shrink)

Different immunotherapeutic approaches are in the pipeline for the treatment of drug dependence. “Drug vaccines” aim to induce the immune system to produce antibodies that bind to drugs and prevent them from inducing rewarding effects in the brain. Drugs of abuse currently being tested using these new approaches are opioids, nicotine, cocaine, and methamphetamine. In human clinical trials, “cocaine and nicotine vaccines” have been shown to induce sufficient antibody levels while producing few side effects. Studies in humans, determining how these (...) vaccines interact in combination with their target drug, are underway. However, although vaccines can become a reasonable treatment option for drugs of abuse, there are several disadvantages that must be considered. These include i) great individual variability in the formation of antibodies, ii) the lack of protection against a structurally dissimilar drug that produces the same effects as the drug of choice, and iii) the lack of an effect on the drug desire that may predispose an addict to relapse. In addition, a comprehensive overview of several crucial ethical issues has not yet been widely discussed in order to have not only a biological approach to immunotherapy of addiction. Overall, immunotherapy offers a range of possible treatment options: the pharmacological treatment of addiction, the treatment of overdoses, the prevention of toxicity to the brain or the heart, and the protection of the fetus during pregnancy. So far, the results obtained from a small-scale experiment using vaccines against cocaine and nicotine suggest that a number of important technical challenges still need to be overcome before such vaccines can be approved for clinical use. (shrink)

Philosophers have long struggled to reconcile Martin Heidegger's involvement in Nazism with his status as one of the greatest thinkers of the twentieth century. The recent publication of his Black Notebooks has reignited fierce debate on the subject. These thousand-odd pages of jotted observations profoundly challenge our image of the quiet philosopher's exile in the Black Forest, revealing the shocking extent of his anti-Semitism for the first time. For much of the philosophical community, the Black Notebooks have been either used (...) to discredit Heidegger or seen as a bibliographical detail irrelevant to his thought. Yet, in this new book, renowned philosopher Donatella Di Cesare argues that Heidegger's "metaphysical anti-Semitism" was a central part of his philosophical project. Within the context of the Nuremberg race laws, Heidegger felt compelled to define Jewishness and its relationship to his concept of Being. Di Cesare shows that Heidegger saw the Jews as the agents of a modernity that had disfigured the spirit of the West. In a deeply disturbing extrapolation, he presented the Holocaust as both a means for the purification of Being and the Jews' own "self-destruction": a process of death on an industrialized scale that was the logical conclusion of the acceleration in technology they themselves had brought about. Situating Heidegger's anti-Semitism firmly within the context of his thought, this groundbreaking work will be essential reading for students and scholars of philosophy and history as well as the many readers interested in Heidegger's life, work, and legacy. (shrink)